Computational genomics of marine biodiversity and ecosystem function Marine ecosystems contain vast biodiversity. Our research uses advanced genomics and computational approaches to understand genome evolution across diverse marine lineages, including microbes, harmful algae, corals, and jellyfish, with a focus on…
Bioinformatics for rapid in-field detection of viruses in animal and environmental samples Rapid decentralised viral testing is becoming essential in environmental and agricultural settings because results are often needed at the point of sampling. Viral bioinformatics helps identify the best…
Improving Performance, Robustness and Interpretability of H&E-Based Models in Spatial Pathology Spatial transcriptomics (ST) links tissue morphology with gene expression, enabling new opportunities for computational pathology and precision medicine. However, ST technologies remain costly and difficult to scale clinically. Predicting…
The changing landscape of research computing …. and what that means for scientists The ecosystem of data and analysis is rapidly changing, and affected by AI, cybersecurity and the complexities of organisational change. Learn about what to consider at a…
Precision health, cohort genomics and translational research The Genomics Research Centre at QUT undertakes research aimed at identifying the genes involved in a variety of complex traits and disorders, with a focus on neurogenetic and cerebrovascular disorders. The Centre has…
Deriving Clinical Insights from Spatial Proteomics and Spatial Transcriptomics Data Spatial proteomics and spatial transcriptomic profiles of the tumour microenvironment provide a rich trove of biological information of the dynamic processes underlying cancer progression, however deciphering clinically relevant information from…
A systems-based approach to schizophrenia: integrating patient-derived olfactory neural stem cells and multi-omics for personalised therapy Alexandre S. Cristino(1)(1) Neurogenomics and Systems Biology Lab, Institute for Biomedicine and Glycomics, School of Environment and Science, Griffith University, Nathan, QLD, 4111 Schizophrenia…
Beyond Bioinformatics – Revisiting Linear Interaction Energy (LIE) for Virtual Screening in Drug Design The end-goal of bioinformatics-based approach per se and in conjunction with experiments is the identification and validation of potential therapeutic target(s). The next challenging step is…
Building the Structural Evolutionary Toolkit of Tomorrow Protein sequences lie. At the twilight zone of sequence identity, where homology detection fails and alignments collapse, evolution has quietly preserved something far more fundamental: the fold. In the post-AlphaFold era, where structural…
Genos and Beyond: From Scalable AI Infrastructure to Multi-Omics Data Analysis This talk introduces Genos, a large open-source human-centric genomic foundation model that learns directly from high-quality human genomes representing global ancestries and scales to single-nucleotide precision across ultra-long contexts….
What You Can’t See Can Hurt You:Uncovering Regulatory Off-Target Effects in CRISPR-Edited Genomes Brad Balderson*, Michael H. Lorenzini*, Shanna N. Lavalle, Karthyayani Sajeev, Aaron J. Ho, Madelyn Light, Olalekan H. Usman, Gavin Kurgan, Graham McVicker *co-first authors A longstanding barrier…
SpaNorm, SpaNormSVG, and SpiDE: A Spatial Transcriptomics Toolkit for Atlas-Scale TME Characterisation and Clinical Response Prediction in Non-Small Cell Lung Cancer Spatial transcriptomics is transforming our ability to interrogate tumour ecosystems in situ, yet integrating high-dimensional molecular data with pathology…
Using AI Effectively and Ethically in Learning: Preparing Students for the Real World The rapid adoption of generative AI tools is transforming how students learn, solve problems, and engage with knowledge. While these tools offer significant opportunities, they also introduce…
Beyond the pipeline: building bioinformatics workflows for non-bioinformaticians Dr. Magdalena Antczak1, Dr. Cameron J Hyde2, Lanxi (Daisy) Li2, Valentine Murigneux1, Dr. Sarah Williams1, W C Mike Thang1, Bradley Pease3, Shaun Bochow3, Grace Sun3 Creating bioinformatics workflows that can be adopted…
Hidden Genes: Bioinformatics, CRISPR and lncRNAs in Cancer Long noncoding RNAs (lncRNAs) are a vast and largely unexplored class of genes that regulate gene expression and cancer biology. My research focuses on understanding how lncRNAs contribute to women’s cancers, particularly…
The role of bioinformatics at the Public and Environmental Health Reference Laboratories (PEHRL) in Queensland The Public and Environmental Health Reference Laboratories (PEHRL) in Queensland play a critical role in supporting public health surveillance, outbreak investigation, and environmental monitoring across…
Meta-tools for metagenomics: integrating tools for next-generation analysis Recovering and analysing microbial genomes from metagenomes depends on a growing set of specialised software, but mixing and matching these tools together into “meta” workflows can push the boundaries of analysis even…
Cracking the Carapace: Transcriptomic Insights for Crustacean Aquaculture Crustaceans display remarkable physiological adaptations, yet many of the molecular mechanisms governing these processes remain poorly understood. By applying transcriptomics across a range of species, we have investigated gene expression associated with…
Clinical Bioinformatics at Pathology Queensland This talk will give an overview of human bioinformatics within the Genomics Discipline at Pathology Queensland, and outline where the service stands today. The service runs custom-built pipelines incorporating both open-source and commercial components for…
Transcriptomic characterisation of eyestalk and central nervous system during ovarian maturation in black tiger prawn Centre for Bioinnovation and School of Science, Technology and EngineeringUniversity of the Sunshine Coast, Sippy Downs, QLD 4556 Successful reproduction in captive female black tiger…
From Bioinformatics to Industry ML: What Transfers, What Changes In this short talk, I’ll share how I moved from bioinformatics into an industry Data Scientist / ML Engineer role at Truckit.net, where I apply machine learning to a freight marketplace….
Digital Research & Technology Services by Intersect Intersect delivers comprehensive Research Solutions by integrating people, expertise, and technology to support the entire research lifecycle. As Australia’s largest eResearch services provider, Intersect’s core mission is to solve complex research problems. This…
Building Bioinformatics Capability: Support, Training and Mentorship Bioinformatics is now integral to research, yet many researchers face challenges accessing the expertise, training, and resources needed to fully leverage their data. This presentation will explore how integrated support, practical training, and…
Exploring the intersection of bioinformatics and AI in healthcare: Opportunities and challenges The intersection of bioinformatics and AI is revolutionizing healthcare in terms of precision medicine, drug discovery and development, multi-omics data integration and predictive modelling and synthetic biology. But…
The Future of Queensland Bioinformatics is People – How to Create A Stronger Community? In this 10min window, I will highlight how our greatest strength for a vibrant Queensland bioinformatics future lies with our people. But how can we work…
Data are a pre-requisite but bioinformatics enables scientific discovery The proliferation of technologies brings biological data at ever-greater scale and resolution. To gain accurate insights, we analyse resulting data sets in combination, and by incorporating biological expertise often gained from…
Genomics of wild Oceanian citrus species and their use in breeding programs Citrus is one of the world’s most valuable fruit tree crops, yet elite cultivars carry limited genetic diversity, leaving them vulnerable to disease and environmental stress. Wild Oceanian…
The Genome Taxonomy Database (GTDB) in 2026 Bio Professor Phil Hugenholtz is a microbiologist who heads the Australian Centre for Ecogenomics. He has made significant contributions in the field of culture-independent analysis of microorganisms. He discovered and characterised numerous previously…
Tim Mercer specialises in genomics, transcriptomics and synthetic biology. Professor Timothy Mercer is a Group Leader at the Australian Institute for Bioengineering and Nanotechnology (AIBN) at The University of Queensland where he is the Scientific Director of the BASE nucleic-acid…
Uncovering the role of alternative splicing and isoforms in cell fate and disease Alternative splicing (AS) is a fundamental mechanism of gene regulation that generates multiple isoforms from a single gene, thereby expanding transcript and protein diversity in eukaryotic cells….
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