Bioinformatics for rapid in-field detection of viruses in animal and environmental samples
Rapid decentralised viral testing is becoming essential in environmental and agricultural settings because results are often needed at the point of sampling. Viral bioinformatics helps identify the best genetic targets for these tests and supports the design of assays that work across many sample types. These samples can include animal tissues and fluids, crushed mosquitoes, and environmental water. Two simple workflows now allow testing outside a traditional laboratory. Both rely on our novel TNA-Cifer Reagent E, which releases viral nucleic acids quickly and removes the need for complex extraction equipment. One workflow uses TNA-Cifer Reagent E with a small semi-automated robotic system and fast PCR instruments to provide accurate testing near the sampling site. The other workflow uses TNA-Cifer Reagent E with isothermal amplification and a lateral flow strip, which needs only a heating block and basic pipettes. Together, these approaches show how bioinformatics can support development of practical molecular tests for surveillance across environmental, agricultural and ecosystem health settings.
Bio
Dr. Joanne Macdonald is Associate Professor, Molecular Engineering at the University of the Sunshine Coast. She is also the founder and Chief Technology Officer of BioCifer Pty Ltd. Dr. Macdonald leads the development of rapid, field-ready molecular diagnostics, including BioCifer’s first commercial product that enables rapid and accurate on-site PCR testing. She is currently working with industry partners to deploy on-farm testing systems in Australian piggeries to strengthen early disease detection and biosecurity. Her work focuses on advancing biotechnology to protect human and animal health through accessible, high-impact diagnostic solutions.
